7VKR
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7VKK
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7VKQ
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7DMQ
| Cryo-EM structure of LshCas13a-crRNA-anti-tag RNA complex | 分子名称: | Anti-tag target RNA, CRISPR RNA, CRISPR/Cas system Cas13a | 著者 | Wang, B, Zhang, T, Ding, J, Patel, D.J, Yang, H. | 登録日 | 2020-12-05 | 公開日 | 2021-02-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems. Mol.Cell, 81, 2021
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8JKQ
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8JKN
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8JKL
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8JKO
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8JKS
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8JYV
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8JYW
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8JYZ
| Cryo-EM structure of RCD-1 pore from Neurospora crassa | 分子名称: | Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2 | 著者 | Hou, Y.J, Sun, Q, Li, Y, Ding, J. | 登録日 | 2023-07-04 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms. Science, 384, 2024
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8JYX
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8JYY
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8J6K
| Crystal structure of pro-interleukin-18 and caspase-4 complex | 分子名称: | Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ... | 著者 | Sun, Q, Hou, Y.J, Ding, J. | 登録日 | 2023-04-26 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome. Nature, 624, 2023
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4RL2
| Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins | 分子名称: | (1R)-2-({(R)-carboxy[(2R,5S)-4-carboxy-5-methyl-5,6-dihydro-2H-1,3-thiazin-2-yl]methyl}amino)-2-oxo-1-phenylethanaminium, Beta-lactamase NDM-1, ZINC ION | 著者 | Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W. | 登録日 | 2014-10-15 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.008 Å) | 主引用文献 | Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins. J.Am.Chem.Soc., 136, 2014
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4RM5
| Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins | 分子名称: | Beta-lactamase NDM-1, ZINC ION | 著者 | Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W. | 登録日 | 2014-10-19 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins. J.Am.Chem.Soc., 136, 2014
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7VUX
| Complex structure of PD1 and 609A-Fab | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X. | 登録日 | 2021-11-04 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties. Mabs, 14, 2022
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7E1T
| Crystal structure of Rab9A-GTP-Nde1 | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Isoform 2 of Nuclear distribution protein nudE homolog 1, MAGNESIUM ION, ... | 著者 | Zhang, Y, Zhang, T, Ding, J. | 登録日 | 2021-02-03 | 公開日 | 2021-10-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex. Structure, 30, 2022
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5Y38
| Crystal structure of C7orf59-HBXIP complex | 分子名称: | Ragulator complex protein LAMTOR4, Ragulator complex protein LAMTOR5, SULFATE ION | 著者 | Zhang, T, Ding, J. | 登録日 | 2017-07-28 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017
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5Y39
| Crystal structure of Ragulator complex (p18 76-145) | 分子名称: | Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... | 著者 | Zhang, T, Ding, J. | 登録日 | 2017-07-28 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017
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5Y3A
| Crystal structure of Ragulator complex (p18 49-161) | 分子名称: | Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... | 著者 | Zhang, T, Ding, J. | 登録日 | 2017-07-28 | 公開日 | 2017-12-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1. Nat Commun, 8, 2017
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4M6W
| Crystal structure of the C-terminal segment of FANCM in complex with FAAP24 | 分子名称: | Fanconi anemia group M protein, Fanconi anemia-associated protein of 24 kDa, SULFATE ION | 著者 | Yang, H, Zhang, T, Tong, L, Ding, J. | 登録日 | 2013-08-11 | 公開日 | 2013-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair. Nucleic Acids Res., 41, 2013
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7WR1
| P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain | 分子名称: | Caspase-4, OspC3 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR4
| Crystal structure of OspC3-calmodulin-caspase-4 complex | 分子名称: | Calmodulin-1, Caspase-4, OspC3 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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