7DMQ

Cryo-EM structure of LshCas13a-crRNA-anti-tag RNA complex

Summary for 7DMQ

Entry DOI	10.2210/pdb7dmq/pdb
EMDB information	30767
Descriptor	CRISPR/Cas system Cas13a, CRISPR RNA, Anti-tag target RNA (3 entities in total)
Functional Keywords	type vi-a crispr-cas system, cas13a, anti-tag rna, inhibition, immune system, immune system-rna complex, immune system/rna
Biological source	Leptotrichia shahii More
Total number of polymer chains	3
Total formula weight	197146.77
Authors	Wang, B.,Zhang, T.,Ding, J.,Patel, D.J.,Yang, H. (deposition date: 2020-12-05, release date: 2021-02-10, Last modification date: 2024-03-27)
Primary citation	Wang, B.,Zhang, T.,Yin, J.,Yu, Y.,Xu, W.,Ding, J.,Patel, D.J.,Yang, H. Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems. Mol.Cell, 81:1100-, 2021 Cited by PubMed: 33472057 DOI: 10.1016/j.molcel.2020.12.033 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.06 Å)

Structure validation