7DMQ

Cryo-EM structure of LshCas13a-crRNA-anti-tag RNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0051607	biological_process	defense response to virus

Functional Information from PROSITE/UniProt

site_id	PS00268
Number of Residues	9
Details	CECROPIN Cecropin family signature. W..NITKRIEK

Chain	Residue	Details
A	TRP305-LYS313

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: For pre-crRNA processing => ECO:0000305|PubMed:28086085

Chain	Residue	Details
A	ARG438
A	LYS441

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: For target ssRNA cleavage => ECO:0000305|PubMed:27256883

Chain	Residue	Details
A	ARG597
A	HIS602
A	ARG1278
A	HIS1283

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site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:28086085

Chain	Residue	Details
A	ARG219
A	LYS441
A	LYS489
A	GLN759
A	TRP865

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