7WR1

P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain

Summary for 7WR1

• Entry DOI: 10.2210/pdb7wr1/pdb
• Descriptor: Caspase-4, OspC3 (3 entities in total)
• Functional Keywords: adp-riboxanase, effector, ankyrin-repeat domain, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 100923.28

Authors

Hou, Y.J.,Zeng, H.,Shao, F.,Ding, J. (deposition date: 2022-01-26, release date: 2023-01-25, Last modification date: 2023-11-29)

• Primary citation: Hou, Y.,Zeng, H.,Li, Z.,Feng, N.,Meng, F.,Xu, Y.,Li, L.,Shao, F.,Ding, J.; Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.; Nat.Struct.Mol.Biol., 30:261-272, 2023; PubMed: 36624349; DOI: 10.1038/s41594-022-00888-3

Experimental method

X-RAY DIFFRACTION (2.13 Å)