7WR1
P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HkssdStfLvLMSHG |
| Chain | Residue | Details |
| A | HIS197-GLY211 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P29466 |
| Chain | Residue | Details |
| A | HIS210 | |
| B | HIS210 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:22246630, ECO:0000269|PubMed:23661706, ECO:0000269|PubMed:25119034, ECO:0000269|PubMed:37993712, ECO:0000269|PubMed:37993714, ECO:0000269|PubMed:7743998 |
| Chain | Residue | Details |
| A | ALA258 | |
| B | ALA258 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:37993714, ECO:0000269|PubMed:7797510 |
| Chain | Residue | Details |
| A | ASP289 | |
| B | ASP289 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: (Microbial infection) ADP-riboxanated arginine => ECO:0000269|PubMed:34671164, ECO:0000269|PubMed:35338844, ECO:0000269|PubMed:36624349 |
| Chain | Residue | Details |
| A | ARG314 | |
| B | ARG314 |
