7WR1

P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Caspase-4	polymer	280	32095.4	2	UniProt (P49662) Pfam (PF00656)	Homo sapiens (human)	CASP-4
2	C, D (C, D)	OspC3	polymer	161	18366.2	2	UniProt (R4X5L7) Pfam (PF06128) UniProt (by SIFTS) (A0A0H2US87)	Shigella flexneri
3	E, F, G, H (A, B, C, D)	water	water		18.0	508	Chemie (HOH)

Sequence modifications

A, B: 102 - 377 (UniProt: P49662)

PDB	External Database	Details
Ser 98	-	expression tag
Gly 99	-	expression tag
Arg 100	-	expression tag
Pro 101	-	expression tag
Ala 258	Cys 258	engineered mutation

C, D: 332 - 484 (UniProt: R4X5L7)

PDB	External Database	Details
Gly 324	-	expression tag
Pro 325	-	expression tag
Leu 326	-	expression tag
Gly 327	-	expression tag
Ser 328	-	expression tag
Gly 329	-	expression tag
Arg 330	-	expression tag
Pro 331	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	100923.3
All*	Total formula weight	100923.3

*Water molecules are not included.