8TZP
| Structure of human Wnt7a bound to WLS and RECK | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PALMITOLEIC ACID, Protein Wnt-7a, ... | Authors: | Qi, X, Hu, Q, Li, X. | Deposit date: | 2023-08-27 | Release date: | 2023-10-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling. Cell, 186, 2023
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8TZS
| Structure of human WLS | Descriptor: | Protein wntless homolog | Authors: | Qi, X, Hu, Q, Li, X. | Deposit date: | 2023-08-27 | Release date: | 2023-10-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling. Cell, 186, 2023
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8TZR
| Structure of human Wnt3a bound to WLS and CALR | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calreticulin, PALMITOLEIC ACID, ... | Authors: | Qi, X, Hu, Q, Li, X. | Deposit date: | 2023-08-27 | Release date: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of human Wnt3a bound to WLS and CALR To Be Published
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6OEU
| Structure of human Patched1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1 | Authors: | Qi, X, Li, X, Wang, J. | Deposit date: | 2019-03-27 | Release date: | 2019-04-10 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of human Patched and its complex with native palmitoylated sonic hedgehog. Nature, 560, 2018
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7URC
| Human PORCN in complex with LGK974 | Descriptor: | 2-[(2P)-2',3-dimethyl[2,4'-bipyridin]-5-yl]-N-[(5P)-5-(pyrazin-2-yl)pyridin-2-yl]acetamide, 2C11 heavy chain, 2C11 light chain, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URE
| Human PORCN in complex with palmitoleoylated WNT3A peptide | Descriptor: | 2C11 heavy chain, 2C11 light chain, Digitonin, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URD
| Human PORCN in complex with LGK974 and WNT3A peptide | Descriptor: | 2-[(2P)-2',3-dimethyl[2,4'-bipyridin]-5-yl]-N-[(5P)-5-(pyrazin-2-yl)pyridin-2-yl]acetamide, 2C11 heavy chain, 2C11 light chain, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URA
| Human PORCN in complex with Palmitoleoyl-CoA | Descriptor: | 2C11 heavy chain, 2C11 light chain, CHOLESTEROL, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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7URF
| Human HHAT H379C in complex with SHH N-terminal peptide | Descriptor: | 3H02 heavy chain, 3H02 light chain, Digitonin, ... | Authors: | Liu, Y, Qi, X, Li, X. | Deposit date: | 2022-04-21 | Release date: | 2022-07-20 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation. Nature, 607, 2022
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3V32
| Crystal structure of MCPIP1 N-terminal conserved domain | Descriptor: | Ribonuclease ZC3H12A | Authors: | Xu, J, Peng, W, Sun, Y, Wang, X, Xu, Y, Li, X, Gao, G, Rao, Z. | Deposit date: | 2011-12-12 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase Nucleic Acids Res., 40, 2012
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6OT0
| Structure of human Smoothened-Gi complex | Descriptor: | 17-[3-(3,3-DIMETHYL-OXIRANYL)-1-METHYL-PROPYL]-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-OL, Fab heavy chain, Fab light chain, ... | Authors: | Qi, X, Li, X. | Deposit date: | 2019-05-02 | Release date: | 2019-06-12 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi. Nature, 571, 2019
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7SHN
| Cryo-EM structure of oleoyl-CoA-bound human peroxisomal fatty acid transporter ABCD1 | Descriptor: | ATP-binding cassette sub-family D member 1, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name) | Authors: | Wang, R, Li, X. | Deposit date: | 2021-10-09 | Release date: | 2021-11-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of acyl-CoA transport across the peroxisomal membrane by human ABCD1. Cell Res., 32, 2022
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7SHM
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6OEV
| Structure of human Patched1 in complex with native Sonic Hedgehog | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1, ... | Authors: | Qi, X, Li, X. | Deposit date: | 2019-03-27 | Release date: | 2019-04-17 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of human Patched and its complex with native palmitoylated sonic hedgehog. Nature, 560, 2018
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3V34
| Crystal structure of MCPIP1 conserved domain with magnesium ion in the catalytic center | Descriptor: | MAGNESIUM ION, Ribonuclease ZC3H12A | Authors: | Xu, J, Peng, W, Sun, Y, Wang, X, Xu, Y, Li, X, Gao, G, Rao, Z. | Deposit date: | 2011-12-12 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase Nucleic Acids Res., 40, 2012
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3V33
| Crystal structure of MCPIP1 conserved domain with zinc-finger motif | Descriptor: | Ribonuclease ZC3H12A | Authors: | Xu, J, Peng, W, Sun, Y, Wang, X, Xu, Y, Li, X, Gao, G, Rao, Z. | Deposit date: | 2011-12-12 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase Nucleic Acids Res., 40, 2012
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3CTM
| Crystal Structure of a Carbonyl Reductase from Candida Parapsilosis with anti-Prelog Stereo-specificity | Descriptor: | Carbonyl Reductase | Authors: | Zhang, R, Zhu, G, Li, X, Xu, Y, Zhang, X.C, Rao, Z. | Deposit date: | 2008-04-14 | Release date: | 2008-05-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity. Protein Sci., 17, 2008
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8DJM
| HMGCR-UBIAD1 Complex State 1 | Descriptor: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, CHOLESTEROL HEMISUCCINATE, Digitonin, ... | Authors: | Chen, H, Qi, X, Li, X. | Deposit date: | 2022-07-01 | Release date: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain. Nat Commun, 13, 2022
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8DJK
| HMGCR-UBIAD1 Complex State 2 | Descriptor: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, CHOLESTEROL HEMISUCCINATE, Digitonin, ... | Authors: | Chen, H, Qi, X, Li, X. | Deposit date: | 2022-06-30 | Release date: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain. Nat Commun, 13, 2022
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3QQ3
| Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides | Descriptor: | 9-mer peptide from Neuraminidase, Beta-2-microglobulin, MHC class I antigen | Authors: | Zhang, N, Qi, J, Gao, F, Pan, X, Chen, R, Li, Q, Chen, Z, Li, X, Xia, C, Gao, G.F. | Deposit date: | 2011-02-15 | Release date: | 2011-12-28 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides. J.Virol., 85, 2011
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3QQ4
| Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides | Descriptor: | Beta-2-microglobulin, MHC class I antigen, VP35 | Authors: | Zhang, N, Qi, J, Gao, F, Pan, X, Chen, R, Li, Q, Chen, Z, Li, X, Xia, C, Gao, G.F. | Deposit date: | 2011-02-15 | Release date: | 2011-12-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides. J.Virol., 85, 2011
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1VM5
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1VM3
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1VM2
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1VM4
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