8FN4

Cryo-EM structure of RNase-treated RESC-A in trypanosomal RNA editing

Summary for 8FN4

Entry DOI	10.2210/pdb8fn4/pdb
EMDB information	29305
Descriptor	RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), RNA-editing substrate-binding complex protein 3 (RESC3), ... (6 entities in total)
Functional Keywords	heat repeat, trypanosoma, rna editing substrate binding complex, grna, rna binding protein-rna complex, rna binding protein/rna
Biological source	Trypanosoma brucei More
Total number of polymer chains	6
Total formula weight	383422.30
Authors	Liu, S.,Wang, H.,Li, X.,Zhang, F.,Lee, J.K.J.,Li, Z.,Yu, C.,Zhao, X.,Hu, J.J.,Suematsu, T.,Alvarez-Cabrera, A.L.,Liu, Q.,Zhang, L.,Huang, L.,Aphasizheva, I.,Aphasizhev, R.,Zhou, Z.H. (deposition date: 2022-12-26, release date: 2023-07-19)
Primary citation	Liu, S.,Wang, H.,Li, X.,Zhang, F.,Lee, J.K.J.,Li, Z.,Yu, C.,Hu, J.J.,Zhao, X.,Suematsu, T.,Alvarez-Cabrera, A.L.,Liu, Q.,Zhang, L.,Huang, L.,Aphasizheva, I.,Aphasizhev, R.,Zhou, Z.H. Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381:eadg4725-eadg4725, 2023 Cited by PubMed: 37410820 DOI: 10.1126/science.adg4725 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation