4EHP
Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
Summary for 4EHP
Entry DOI | 10.2210/pdb4ehp/pdb |
Related | 1rkc 1rke 1syq 1tr2 1ydi 2gww 2hsq 2ibf 3h2u 3h2v 3myi 3rf3 3s90 3smz 3tj5 3tj6 4dj9 |
Descriptor | Vinculin, Catenin alpha-1, ACETATE ION, ... (4 entities in total) |
Functional Keywords | adherens junctions, vinculin binding site, vinculin binding domain, helix bundle, cell adhesion |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: P18206 P35221 |
Total number of polymer chains | 2 |
Total formula weight | 41349.35 |
Authors | Izard, T.,Rangarajan, E.S. (deposition date: 2012-04-03, release date: 2012-04-18, Last modification date: 2023-09-13) |
Primary citation | Rangarajan, E.S.,Izard, T. alpha-Catenin unfurls upon binding to vinculin J.Biol.Chem., 287:18492-18499, 2012 Cited by PubMed: 22493458DOI: 10.1074/jbc.M112.351023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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