Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0005198 | molecular_function | structural molecule activity |
| A | 0007155 | biological_process | cell adhesion |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0051015 | molecular_function | actin filament binding |
| B | 0007155 | biological_process | cell adhesion |
| B | 0045296 | molecular_function | cadherin binding |
| B | 0051015 | molecular_function | actin filament binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 301 |
| Chain | Residue |
| A | THR6 |
| A | ILE9 |
| A | ASP127 |
| A | HOH447 |
| B | ARG330 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 302 |
| Chain | Residue |
| A | ASP39 |
| A | LEU250 |
| A | THR251 |
| A | SER252 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 303 |
| Chain | Residue |
| A | ILE245 |
| A | GLN249 |
| A | HOH454 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 304 |
| Chain | Residue |
| A | SER207 |
| A | LYS228 |
| A | ASN229 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 305 |
| Chain | Residue |
| A | VAL32 |
| A | LYS35 |
| A | TYR100 |
| A | SER101 |
| A | ARG105 |
| B | TYR351 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 306 |
| Chain | Residue |
| A | THR197 |
| A | GLU200 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 307 |
| Chain | Residue |
| A | THR65 |
| A | PHE126 |
| A | LYS133 |
| B | ARG329 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 308 |
| Chain | Residue |
| A | LYS87 |
| A | ASP110 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 309 |
| Chain | Residue |
| A | PRO2 |
| A | GLN90 |
| A | TYR107 |
| A | THR183 |
| A | GLN185 |
| A | GLU186 |
Functional Information from PROSITE/UniProt
| site_id | PS00663 |
| Number of Residues | 21 |
| Details | VINCULIN_1 Vinculin family talin-binding region signature. KnLgpgMtkMakmideRQQEL |
| Chain | Residue | Details |
| A | LYS162-LEU182 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Region: {"description":"Talin-interaction","evidences":[{"source":"UniProtKB","id":"P12003","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P85972","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
