4ANK

Crystallographic study of novel transthyretin ligands exhibiting negative-cooperativity between two T4 binding sites.

4ANK の概要

• エントリーDOI: 10.2210/pdb4ank/pdb
• 関連するPDBエントリー: 1BM7 1BMZ 1BZ8 1BZD 1BZE 1DVQ 1DVS 1DVT 1DVU 1DVX 1DVY 1DVZ 1E3F 1E4H 1E5A 1ETA 1ETB 1F41 1F64 1F86 1FH2 1FHN 1G1O 1GKO 1ICT 1III 1IIK 1IJN 1QAB 1QWH 1RLB 1SOK 1SOQ 1THA 1THC 1TLM 1TSH 1TT6 1TTA 1TTB 1TTC 1TTR 1TYR 1TZ8 1U21 1X7S 1X7T 1Y1D 1Z7J 1ZCR 1ZD6 2B14 2B15 2B16 2B77 2B9A 2F7I 2F8I 2FBR 2FLM 2G5U 2G9K 2GAB 2PAB 2ROX 2ROY 2TRH 2TRY 2WQA 4ABQ 4ABU 4ABV 4ABW 4AC2 4AC4 4ACT 5TTR
• 分子名称: TRANSTHYRETIN (2 entities in total)
• 機能のキーワード: hormone binding protein, thyroxine transport protein, hormone, amyloidosis inhibition
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31809.97

構造登録者

Tomar, D.,Khan, T.,Singh, R.R.,Mishra, S.,Gupta, S.,Surolia, A.,Salunke, D.M. (登録日: 2012-03-20, 公開日: 2012-09-26, 最終更新日: 2023-12-20)

• 主引用文献: Tomar, D.,Khan, T.,Singh, R.R.,Mishra, S.,Gupta, S.,Surolia, A.,Salunke, D.M.; Crystallographic Study of Novel Transthyretin Ligands Exhibiting Negative-Cooperativity between Two Thyroxine Binding Sites.; Plos One, 7:43522-, 2012; PubMed: 22973437; DOI: 10.1371/JOURNAL.PONE.0043522

実験手法

X-RAY DIFFRACTION (1.7 Å)