1TZ8

The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol

Summary for 1TZ8

Entry DOI	10.2210/pdb1tz8/pdb
Related	1TT6
Descriptor	Transthyretin, ACETATE ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
Functional Keywords	amyloid, transthyretin, diethylstilbestrol, protein stabilization, transport protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	4
Total formula weight	56295.86
Authors	Morais-de-Sa, E.M.,Pereira, P.J.B.,Saraiva, M.J.,Damas, A.M. (deposition date: 2004-07-09, release date: 2004-10-12, Last modification date: 2023-08-23)
Primary citation	Morais-de-Sa, E.M.,Pereira, P.J.B.,Saraiva, M.J.,Damas, A.M. The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279:53483-53490, 2004 Cited by PubMed: 15469931 DOI: 10.1074/jbc.M408053200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation