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5TTR

LEU 55 PRO TRANSTHYRETIN CRYSTAL STRUCTURE

Summary for 5TTR
Entry DOI10.2210/pdb5ttr/pdb
DescriptorTRANSTHYRETIN (1 entity in total)
Functional Keywordstransthyretin, amyloid, fap, thyroxine, transport
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains8
Total formula weight110090.54
Authors
Sebastiao, M.P.,Saraiva, M.J.,Damas, A.M. (deposition date: 1998-04-30, release date: 1999-06-01, Last modification date: 2023-08-09)
Primary citationSebastiao, M.P.,Saraiva, M.J.,Damas, A.M.
The crystal structure of amyloidogenic Leu55 --> Pro transthyretin variant reveals a possible pathway for transthyretin polymerization into amyloid fibrils.
J.Biol.Chem., 273:24715-24722, 1998
Cited by
PubMed: 9733771
DOI: 10.1074/jbc.273.38.24715
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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