1Y1D

Crystal structure of transthyretin in complex with iododiflunisal

Summary for 1Y1D

Entry DOI	10.2210/pdb1y1d/pdb
Descriptor	Transthyretin, 2',4'-DIFLUORO-4-HYDROXY-5-IODO-1,1'-BIPHENYL-3-CARBOXYLIC ACID (3 entities in total)
Functional Keywords	transthyretin, amyloid, iododiflunisal, transport protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	28306.91
Authors	Gales, L.,Macedo-Ribeiro, S.,Arsequell, G.,Valencia, G.,Saraiva, M.J.,Damas, A.M. (deposition date: 2004-11-18, release date: 2005-07-26, Last modification date: 2023-08-23)
Primary citation	Gales, L.,Macedo-Ribeiro, S.,Arsequell, G.,Valencia, G.,Saraiva, M.J.,Damas, A.M. Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor. Biochem.J., 388:615-621, 2005 Cited by PubMed: 15689188 DOI: 10.1042/BJ20042035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation