1X7S
The X-ray crystallographic structure of the amyloidogenic variant TTR Tyr78Phe
Summary for 1X7S
Entry DOI | 10.2210/pdb1x7s/pdb |
Related | 1X7T |
Descriptor | Transthyretin (2 entities in total) |
Functional Keywords | transthyretin, familial amyoidotic polyneuropathy, amyloid, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 27522.72 |
Authors | Neto-Silva, R.M.,Macedo-Ribeiro, S.,Pereira, P.J.B.,Saraiva, M.J.,Damas, A.M. (deposition date: 2004-08-16, release date: 2005-03-22, Last modification date: 2023-08-23) |
Primary citation | Neto-Silva, R.M.,Macedo-Ribeiro, S.,Pereira, P.J.,Coll, M.,Saraiva, M.J.,Damas, A.M. X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis. Acta Crystallogr.,Sect.D, 61:333-339, 2005 Cited by PubMed: 15735344DOI: 10.1107/S0907444904034316 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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