1X7S

The X-ray crystallographic structure of the amyloidogenic variant TTR Tyr78Phe

Summary for 1X7S

• Entry DOI: 10.2210/pdb1x7s/pdb
• Related: 1X7T
• Descriptor: Transthyretin (2 entities in total)
• Functional Keywords: transthyretin, familial amyoidotic polyneuropathy, amyloid, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 2
• Total formula weight: 27522.72

Authors

Neto-Silva, R.M.,Macedo-Ribeiro, S.,Pereira, P.J.B.,Saraiva, M.J.,Damas, A.M. (deposition date: 2004-08-16, release date: 2005-03-22, Last modification date: 2023-08-23)

• Primary citation: Neto-Silva, R.M.,Macedo-Ribeiro, S.,Pereira, P.J.,Coll, M.,Saraiva, M.J.,Damas, A.M.; X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis.; Acta Crystallogr.,Sect.D, 61:333-339, 2005; PubMed: 15735344; DOI: 10.1107/S0907444904034316

Experimental method

X-RAY DIFFRACTION (1.55 Å)