2B16

The crystal structure of 2,4-dinitrophenol in complex with the amyloidogenic variant Transthyretin Tyr78Phe

Summary for 2B16

• Entry DOI: 10.2210/pdb2b16/pdb
• Related: 2B14 2B15
• Descriptor: Transthyretin, 2,4-DINITROPHENOL (3 entities in total)
• Functional Keywords: transthyretin, 2, 4-dinitrophenol, amyloid, tetramer stabilizer, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 2
• Total formula weight: 27890.93

Authors

Morais-de-Sa, E.,Neto-Silva, R.M.,Pereira, P.J.,Saraiva, M.J.,Damas, A.M. (deposition date: 2005-09-15, release date: 2006-07-18, Last modification date: 2023-10-25)

• Primary citation: Morais-de-Sa, E.,Neto-Silva, R.M.,Pereira, P.J.,Saraiva, M.J.,Damas, A.M.; The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin; ACTA CRYSTALLOGR.,SECT.D, 62:512-519, 2006; PubMed: 16627944; DOI: 10.1107/S0907444906006962

Experimental method

X-RAY DIFFRACTION (1.75 Å)