2B14

The crystal structure of 2,4-dinitrophenol in complex with the amyloidogenic variant Transthyretin Leu 55 Pro

Summary for 2B14

• Entry DOI: 10.2210/pdb2b14/pdb
• Related: 2B15 2B16
• Descriptor: Transthyretin, 2,4-DINITROPHENOL (3 entities in total)
• Functional Keywords: amyloid, transthyretin, 2, 4-dinitrophenol, tetramer stabilizer, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 2
• Total formula weight: 27890.85

Authors

Morais-de-Sa, E.,Neto-Silva, R.M.,Pereira, P.J.,Saraiva, M.J.,Damas, A.M. (deposition date: 2005-09-15, release date: 2006-07-18, Last modification date: 2023-10-25)

• Primary citation: Morais-de-Sa, E.,Neto-Silva, R.M.,Pereira, P.J.,Saraiva, M.J.,Damas, A.M.; The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin; ACTA CRYSTALLOGR.,SECT.D, 62:512-519, 2006; PubMed: 16627944; DOI: 10.1107/S0907444906006962

Experimental method

X-RAY DIFFRACTION (2 Å)