1G1O
CRYSTAL STRUCTURE OF THE HIGHLY AMYLOIDOGENIC TRANSTHYRETIN MUTANT TTR G53S/E54D/L55S
Summary for 1G1O
Entry DOI | 10.2210/pdb1g1o/pdb |
Descriptor | TRANSTHYRETIN (2 entities in total) |
Functional Keywords | greek key, beta barrel, beta-slip, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 4 |
Total formula weight | 55069.12 |
Authors | Eneqvist, T.,Andersson, K.,Olofsson, A.,Lundgren, E.,Sauer-Eriksson, A.E. (deposition date: 2000-10-13, release date: 2001-10-17, Last modification date: 2024-02-07) |
Primary citation | Eneqvist, T.,Andersson, K.,Olofsson, A.,Lundgren, E.,Sauer-Eriksson, A.E. The beta-slip: a novel concept in transthyretin amyloidosis. Mol.Cell, 6:1207-1218, 2000 Cited by PubMed: 11106758DOI: 10.1016/S1097-2765(00)00117-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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