1F86

TRANSTHYRETIN THR119MET PROTEIN STABILISATION

Summary for 1F86

• Entry DOI: 10.2210/pdb1f86/pdb
• Related: 1TTC
• Descriptor: TRANSTHYRETIN THR119MET VARIANT, 3,5,3',5'-TETRAIODO-L-THYRONINE (3 entities in total)
• Functional Keywords: transthyretin, protein stability, x-ray crystal structure, amyloidogenesis, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 2
• Total formula weight: 26826.13

Authors

Sebastiao, M.P. (deposition date: 2000-06-29, release date: 2001-06-29, Last modification date: 2023-11-15)

• Primary citation: Sebastiao, M.P.,Lamzin, V.,Saraiva, M.J.,Damas, A.M.; Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution.; J.Mol.Biol., 306:733-744, 2001; PubMed: 11243784; DOI: 10.1006/jmbi.2000.4415

Experimental method

X-RAY DIFFRACTION (1.1 Å)