3EOV

Crystal structure of cyclophilin from Leishmania donovani ligated with cyclosporin A

Summary for 3EOV

Related1BCK 1C5F 1CSA 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1CYA 1CYB 1CYN 1IKF 1M63 1MF8 1MIK 1QNG 1QNH 1XQ7 2ESL 2OJU 2POY 2RMA 2RMB 2RMC 2WFJ 2X2C 2X7K 2Z6W 3BO7 3CYS 2HAQ
Related PRD IDPRD_000142
DescriptorPEPTIDYL-PROLYL CIS-TRANS ISOMERASE, CYCLOSPORIN A (3 entities in total)
Functional Keywordsisomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin a, immunosuppressant, cyclophilin, isomerase/immunosuppressant
Biological sourceLEISHMANIA DONOVANI
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Total number of polymer chains4
Total molecular weight40622.33
Authors
Venugopal, V.,Dasgupta, D.,Datta, A.K.,Banerjee, R. (deposition date: 2008-09-29, release date: 2008-11-11, Last modification date: 2012-12-12)
Primary citation
Venugopal, V.,Datta, A.K.,Bhattacharyya, D.,Dasgupta, D.,Banerjee, R.
Structure of Cyclophilin from Leishmania Donovani Bound to Cyclosporin at 2.6 A Resolution: Correlation between Structure and Thermodynamic Data.
Acta Crystallogr.,Sect.D, 65:1187-, 2009
PubMed: 19923714 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444909034234
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.254141.2%2.9%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3eov
no rotation
Molmil generated image of 3eov
rotated about x axis by 90°
Molmil generated image of 3eov
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 3eov
no rotation
Molmil generated image of 3eov
rotated about x axis by 90°
Molmil generated image of 3eov
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3eov.pdb1.gz [30.57 KB])
Coordinate files for Biological unit (3eov.pdb2.gz [30.92 KB])