1C5F

CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A

Replaces:  1QTL

Summary for 1C5F

Related1BCK 1CSA 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1CYA 1CYB 1CYN 1IKF 1M63 1MF8 1MIK 1QNG 1QNH 1XQ7 2ESL 2OJU 2POY 2RMA 2RMB 2RMC 2WFJ 2X2C 2X7K 2Z6W 3BO7 3CYS 3EOV
Related PRD IDPRD_000142
DescriptorPEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1, CYCLOSPORIN A (3 entities in total)
Functional Keywordsisomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin a, immunosuppressant, cyclophilin, isomerase/immunosuppressant
Biological sourceBRUGIA MALAYI
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Total number of polymer chains16
Total molecular weight165800.34
Authors
Ellis, P.J.,Carlow, C.K.S.,Ma, D.,Kuhn, P. (deposition date: 1999-11-22, release date: 1999-12-03, Last modification date: 2017-10-04)
Primary citation
Ellis, P.J.,Carlow, C.K.,Ma, D.,Kuhn, P.
Crystal Structure of the Complex of Brugia Malayi Cyclophilin and Cyclosporin A.
Biochemistry, 39:592-, 2000
PubMed: 10642184 (PDB entries with the same primary citation)
DOI: 10.1021/BI991730Q
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.47 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers110.2%1.8%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12