2RMB

Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A

Summary for 2RMB

Entry DOI	10.2210/pdb2rmb/pdb
Related	1BCK 1C5F 1CSA 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1CYA 1CYB 1CYN 1M63 1MF8 1MIK 1QNG 1QNH 1XQ7 2ESL 2OJU 2POY 2RMA 2RMC 2WFJ 2X2C 2X7K 2Z6W 3BO7 3CYS 3EOV
Related PRD ID	PRD_000765
Descriptor	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, CYCLOSPORIN A (3 entities in total)
Functional Keywords	isomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin a, immunosuppressant, cyclophilin, isomerase/immunosuppressant
Biological source	HOMO SAPIENS More
Cellular location	Cytoplasm : P62937
Total number of polymer chains	20
Total formula weight	192711.55
Authors	Ke, H.,Mayrose, D. (deposition date: 1994-01-07, release date: 1995-02-07, Last modification date: 2017-11-01)
Primary citation	Ke, H.,Mayrose, D.,Belshaw, P.J.,Alberg, D.G.,Schreiber, S.L.,Chang, Z.Y.,Etzkorn, F.A.,Ho, S.,Walsh, C.T. Crystal Structures of Cyclophilin a Complexed with Cyclosporin a and N-Methyl-4-[(E)-2-Butenyl]-4,4-Dimethylthreonine Cyclosporin A. Structure, 2:33-, 1994 Cited by PubMed: 8075981 DOI: 10.1016/S0969-2126(00)00006-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation