1CWM

HUMAN CYCLOPHILIN A COMPLEXED WITH 4 MEILE CYCLOSPORIN

Summary for 1CWM

Related1BCK 1C5F 1CSA 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWO 1CYA 1CYB 1CYN 1IKF 1M63 1MF8 1MIK 1QNG 1QNH 1XQ7 2ESL 2OJU 2POY 2RMA 2RMB 2RMC 2WFJ 2X2C 2X7K 2Z6W 3BO7 3CYS 3EOV
Related PRD IDPRD_000768
DescriptorPEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, CYCLOSPORIN A (3 entities in total)
Functional Keywordsisomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin a, immunosuppressant, cyclophilin, isomerase/immunosuppressant
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationCytoplasm  P62937
Total number of polymer chains2
Total molecular weight19257.13
Authors
Mikol, V.,Kallen, J.,Taylor, P.,Walkinshaw, M.D. (deposition date: 1998-05-26, release date: 1998-07-15, Last modification date: 2018-04-18)
Primary citation
Kallen, J.,Mikol, V.,Taylor, P.,Walkinshaw, M.D.
X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283:435-, 1998
PubMed: 9769216 (PDB entries with the same primary citation)
DOI: 10.1006/JMBI.1998.2108
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers30 6.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-10-21