1CYA

NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING

Summary for 1CYA

Related1BCK 1C5F 1CSA 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1CYB 1CYN 1IKF 1M63 1MF8 1MIK 1QNG 1QNH 1XQ7 2ESL 2OJU 2POY 2RMA 2RMB 2RMC 2WFJ 2X2C 2X7K 2Z6W 3BO7 3CYS 3EOV
Related PRD IDPRD_000142
DescriptorCYCLOSPORIN A (1 entity in total)
Functional Keywordsimmunosuppressant, cyclosporin a
Biological sourceTOLYPOCLADIUM INFLATUM
Total number of polymer chains1
Total molecular weight1220.63
Authors
Fesik, S.W. (deposition date: 1992-02-24, release date: 1994-01-31, Last modification date: 2012-12-12)
Primary citation
Fesik, S.W.,Gampe, R.T.,Eaton, H.L.,Gemmecker, G.,Olejniczak, E.T.,Neri, P.,Holzman, T.F.,Egan, D.A.,Edalji, R.
NMR Studies of [U-13C]Cyclosporin a Bound to Cyclophilin: Bound Conformation and Portions of Cyclosporin Involved in Binding.
Biochemistry, 30:6574-, 1991
PubMed: 2054356 (PDB entries with the same primary citation)
DOI: 10.1021/BI00240A030
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers3100MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures