3EOV

Crystal structure of cyclophilin from Leishmania donovani ligated with cyclosporin A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	polymer	172	19090.5	2	UniProt (Q9U9R3) Pfam (PF00160)	LEISHMANIA DONOVANI	PPIASE, ROTAMASE, CYCLOPHILIN
2	C, D (C, D)	CYCLOSPORIN A	polymer	11	1220.6	2	NOR (NOR00033) BIRD (PRD_000142)	TOLYPOCLADIUM INFLATUM	CICLOSPORIN, CICLOSPORINE
3	E, F, G (A, B, C)	water	water		18.0	76	Chemie (HOH)

Sequence modifications

A, B: 22 - 187 (UniProt: Q9U9R3)

PDB	External Database	Details
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	40622.3
All*	Total formula weight	40622.3

*Water molecules are not included.