1IKF

A CONFORMATION OF CYCLOSPORIN A IN AQUEOUS ENVIRONMENT REVEALED BY THE X-RAY STRUCTURE OF A CYCLOSPORIN-FAB COMPLEX

Summary for 1IKF

Related1BCK 1C5F 1CSA 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1CYA 1CYB 1CYN 1M63 1MF8 1MIK 1QNG 1QNH 1XQ7 2ESL 2OJU 2POY 2RMA 2RMB 2RMC 2WFJ 2X2C 2X7K 2Z6W 3BO7 3CYS 3EOV
Related PRD IDPRD_000142
DescriptorIGG1-KAPPA R45-45-11 FAB (LIGHT CHAIN), IGG1-KAPPA R45-45-11 FAB (HEAVY CHAIN), CYCLOSPORIN A, ... (4 entities in total)
Functional Keywordsimmune system-immunosuppressant complex, fab-cyclosporin complex, cyclosporin a, immunosuppressant, immune system/immunosuppressant
Biological sourceHOMO SAPIENS (HUMAN)
More
Total number of polymer chains3
Total molecular weight49547.51
Authors
Vix, O.,Altschuh, D.,Rees, B.,Thierry, J.-C. (deposition date: 1993-12-09, release date: 1995-03-31, Last modification date: 2012-12-12)
Primary citation
Altschuh, D.,Vix, O.,Rees, B.,Thierry, J.C.
A Conformation of Cyclosporin a in Aqueous Environment Revealed by the X-Ray Structure of a Cyclosporin-Fab Complex.
Science, 256:92-, 1992
PubMed: 1566062 (PDB entries with the same primary citation)
DOI: 10.1126/SCIENCE.1566062
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers110.5%13.0%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution