1IKF

A CONFORMATION OF CYCLOSPORIN A IN AQUEOUS ENVIRONMENT REVEALED BY THE X-RAY STRUCTURE OF A CYCLOSPORIN-FAB COMPLEX

Experimental procedure

Spacegroup name	P 21 21 21
Unit cell lengths	52.600, 70.200, 118.400
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	8.000 - 2.500
R-factor	0.164
Rwork	0.164
RMSD bond length	0.014
RMSD bond angle	3.400
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
High resolution limit [Å]	2.600 *
Rmerge	0.087 *
Total number of observations	63899 *
Number of reflections	14219 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	unknown *