2W9C
Ternary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA with incoming dTTP
Summary for 2W9C
Entry DOI | 10.2210/pdb2w9c/pdb |
Related | 1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2AGO 2AGP 2AGQ 2ASD 2ASJ 2ASL 2ATL 2AU0 2BQ3 2BQR 2BQU 2BR0 2C22 2C28 2C2D 2C2E 2C2R 2J6S 2J6T 2J6U 2JEF 2JEG 2JEI 2JEJ 2UVR 2UVU 2UVV 2UVW 2V4Q 2V4R 2V4S 2V4T 2V9W 2VA2 2VA3 2W8K 2W8L 2W9A 2W9B |
Descriptor | DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*DOCP)-3', 5'-D(*TP*CP*AP*CP*O2GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... (7 entities in total) |
Functional Keywords | dna-directed dna polymerase, n2-dimethyl-g, metal-binding, mutator protein, dna damage, dna repair, dna-binding, transferase, dna replication, nucleotidyltransferase, transferase/dna, dna, dpo4, adduct, cytoplasm, magnesium, polymerase, transferase-dna complex |
Biological source | SULFOLOBUS SOLFATARICUS More |
Cellular location | Cytoplasm (Probable): Q97W02 2W9C |
Total number of polymer chains | 6 |
Total formula weight | 102274.10 |
Authors | Eoff, R.L.,Zhang, H.,Kosekov, I.D.,Rizzo, C.J.,Egli, M.,Guengerich, F.P. (deposition date: 2009-01-22, release date: 2009-05-12, Last modification date: 2023-12-13) |
Primary citation | Zhang, H.,Eoff, R.L.,Kosekov, I.D.,Rizzo, C.J.,Egli, M.,Guengerich, F.P. Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes. J.Biol.Chem., 284:17687-, 2009 Cited by PubMed: 19542237DOI: 10.1074/JBC.M109014274 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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