2VA2
Complex structure of Sulfolobus solfataricus DPO4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand
Summary for 2VA2
Entry DOI | 10.2210/pdb2va2/pdb |
Related | 2V9W 2VA3 |
Descriptor | DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *CP*TP*A)-3', 5'-D(*TP*TP*CP*AP*GP*DFTP*AP*GP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total) |
Functional Keywords | transferase-dna complex, dna-directed dna polymerase, p2 dna polymerase iv, transferase, nucleotidyltransferase, mutator protein, dna replication, dna repair, dna-binding, metal-binding, translesion dna polymerase, 2, ddctp, magnesium, dna damage, transferase/dna |
Biological source | SULFOLOBUS SOLFATARICUS |
Cellular location | Cytoplasm (Probable): Q97W02 |
Total number of polymer chains | 6 |
Total formula weight | 102288.63 |
Authors | Irimia, A.,Pallan, P.S.,Egli, M. (deposition date: 2007-08-28, release date: 2007-10-30, Last modification date: 2023-12-13) |
Primary citation | Irimia, A.,Eoff, R.L.,Pallan, P.S.,Guengerich, F.P.,Egli, M. Structure and Activity of Y-Class DNA Polymerase Dpo4 from Sulfolobus Solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4- Difluorotoluene. J.Biol.Chem., 282:36421-, 2007 Cited by PubMed: 17951245DOI: 10.1074/JBC.M707267200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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