2BR0

DNA Adduct Bypass Polymerization by Sulfolobus solfataricus Dpo4. Analysis and Crystal Structures of Multiple Base-Pair Substitution and Frameshift Products with the Adduct 1,N2-Ethenoguanine

Summary for 2BR0

• Entry DOI: 10.2210/pdb2br0/pdb
• Related: 1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2BQ3 2BQR 2BQU
• Descriptor: DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*C)-3', 5'-D(*TP*CP*AP*CP*GNEP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
• Functional Keywords: p2 dna polymerase iv, 1n2-ethenoguanine adduct, translesion dna polymerase, datp, nucleotidyltransferase, transferase
• Biological source: SULFOLOBUS SOLFATARICUS (SULFOLOBUS SOLFATARICUS)
• Cellular location: Cytoplasm (Probable): Q97W02
• Total number of polymer chains: 3
• Total formula weight: 51047.38

Authors

Irimia, A.,Loukachevitch, L.V.,Egli, M. (deposition date: 2005-04-28, release date: 2005-06-23, Last modification date: 2022-11-02)

• Primary citation: Zang, H.,Goodenough, A.K.,Choi, J.Y.,Irimia, A.,Loukachevitch, L.V.,Kozekov, I.D.,Angel, K.C.,Rizzo, C.J.,Egli, M.,Guengerich, F.P.; DNA Adduct Bypass Polymerization by Sulfolobus Solfataricus DNA Polymerase Dpo4: Analysis and Crystal Structures of Multiple Base Pair Substitution and Frameshift Products with the Adduct 1,N2-Ethenoguanine.; J.Biol.Chem., 280:29750-, 2005; PubMed: 15965231; DOI: 10.1074/JBC.M504756200

Experimental method

X-RAY DIFFRACTION (2.17 Å)