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2UVU

Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs

Summary for 2UVU
Entry DOI10.2210/pdb2uvu/pdb
Related1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2AGO 2AGP 2AGQ 2ASD 2ASJ 2ASL 2ATL 2AU0 2BQ3 2BQR 2BQU 2BR0 2C22 2C28 2C2D 2C2E 2C2R 2J6S 2J6T 2J6U 2JEF 2JEG 2JEI 2JEJ 2UVR 2UVV 2UVW
DescriptorDNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*A)-3', 5'-D(*TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP *CP*TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
Functional Keywordstransferase, dna-directed dna polymerase, p2 dna polymerase iv, nucleotidyltransferase, 7, magnesium, dna damage, dna repair, dna-binding, translesion dna polymerase, metal-binding, 8-dihydro-8- oxodeoxyguanosine, metal- binding, mutator protein, dna replication
Biological sourceSULFOLOBUS SOLFATARICUS
Cellular locationCytoplasm (Probable): Q97W02
Total number of polymer chains3
Total formula weight51426.41
Authors
Irimia, A.,Egli, M. (deposition date: 2007-03-14, release date: 2007-05-08, Last modification date: 2023-12-13)
Primary citationEoff, R.L.,Irimia, A.,Angel, K.C.,Egli, M.,Guengerich, F.P.
Hydrogen Bonding of 7,8-Dihydro-8-Oxodeoxyguanosine with a Charged Residue in the Little Finger Domain Determines Miscoding Events in Sulfolobus Solfataricus DNA Polymerase Dpo4.
J.Biol.Chem., 282:19831-, 2007
Cited by
PubMed: 17468100
DOI: 10.1074/JBC.M702290200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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