2J6T
Ternary complex of Sulfolobus solfataricus Dpo4 DNA polymerase, O6- methylguanine modified DNA, and dATP.
Summary for 2J6T
Entry DOI | 10.2210/pdb2j6t/pdb |
Related | 1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2AGO 2AGP 2AGQ 2ASD 2ASJ 2ASL 2ATL 2AU0 2BQ3 2BQR 2BQU 2BR0 2C22 2C28 2C2D 2C2E 2C2R 2J6S 2J6U |
Descriptor | DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*C)-3', 5'-D(*TP*CP*AP*TP*XP*GP*AP*AP*TP*CP *CP*TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total) |
Functional Keywords | transferase-dna complex, mutator protein, dna replication, o6-methylguanine, transferase, metal-binding, translesion dna synthesis, dna-directed dna polymerase, dpo4, dna repair, dna damage, dna-binding, nucleotidyltransferase, transferase/dna |
Biological source | SULFOLOBUS SOLFATARICUS |
Cellular location | Cytoplasm (Probable): Q97W02 |
Total number of polymer chains | 3 |
Total formula weight | 51196.36 |
Authors | Irimia, A.,Eoff, R.L.,Guengerich, F.P.,Egli, M. (deposition date: 2006-10-04, release date: 2006-11-22, Last modification date: 2023-12-13) |
Primary citation | Eoff, R.L.,Irimia, A.,Egli, M.,Guengerich, F.P. Sulfolobus Solfataricus DNA Polymerase Dpo4 is Partially Inhibited by "Wobble" Pairing between O6- Methylguanine and Cytosine, But Accurate Bypass is Preferred. J.Biol.Chem., 282:1456-, 2007 Cited by PubMed: 17105728DOI: 10.1074/JBC.M609661200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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