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2J6T

Ternary complex of Sulfolobus solfataricus Dpo4 DNA polymerase, O6- methylguanine modified DNA, and dATP.

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0003677molecular_functionDNA binding
A0003684molecular_functiondamaged DNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0005737cellular_componentcytoplasm
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0006281biological_processDNA repair
A0006974biological_processDNA damage response
A0042276biological_processerror-prone translesion synthesis
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 1001
ChainResidue
AASP7
APHE8
AASP105
ADTP1000
AHOH2004

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 1002
ChainResidue
AHOH2025
AASP7
AASP105
AGLU106
ADTP1000

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A 1003
ChainResidue
AALA181
AILE186
AHOH2040
AHOH2041
PHOH2004
PHOH2015

site_idAC4
Number of Residues22
DetailsBINDING SITE FOR RESIDUE DTP A 1000
ChainResidue
APHE8
AASP9
ATYR10
APHE11
ATYR12
AALA44
ATHR45
ATYR48
AARG51
AALA57
AASP105
ALYS159
ACA1001
ACA1002
AHOH2004
AHOH2013
AHOH2061
AHOH2062
AHOH2063
AHOH2064
TDT4
T6OG5

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE:
ChainResidueDetails
AGLU106

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AASP7
AASP105

site_idSWS_FT_FI3
Number of Residues1
DetailsSITE: Substrate discrimination
ChainResidueDetails
ATYR12

226707

PDB entries from 2024-10-30

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