Snapshots of replication through an abasic lesion: structural basis for base substitution and frameshift

Summary for 1S0O

Related1JX4 1RYR 1RYS 1S0M 1S0N 1S10
Descriptor5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*C)-3', 5'-D(*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', DNA polymerase IV, ... (7 entities in total)
Functional Keywordsabaic lesion, lesion bypass, polymerase, transferase-dna complex, transferase/dna
Biological sourceSulfolobus solfataricus
Cellular locationCytoplasm  Q97W02
Total number of polymer chains6
Total molecular weight100081.06
Ling, H.,Boudsocq, F.,Woodgate, R.,Yang, W. (deposition date: 2003-12-31, release date: 2004-03-30, Last modification date: 2018-04-04)
Primary citation
Ling, H.,Boudsocq, F.,Woodgate, R.,Yang, W.
Snapshots of Replication through an Abasic Lesion; Structural Basis for Base Substitutions and Frameshifts.
Mol.Cell, 13:751-762, 2004
PubMed: 15023344 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(04)00101-7
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25716 0.6% 2.0% 3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28