1S0M

Crystal structure of a Benzo[a]pyrene Diol Epoxide adduct in a ternary complex with a DNA polymerase

Summary for 1S0M

• Entry DOI: 10.2210/pdb1s0m/pdb
• Related: 1JX4 1RYR 1RYS 1S0N 1S0O 1S10
• Descriptor: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*T)-3', 5'-D(P*AP*TP*AP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*CP*A)-3', DNA polymerase IV, ... (8 entities in total)
• Functional Keywords: benzo pyrene, carcinogen, lesion bypass, polymerase, transferase-dna complex, transferase/dna
• Biological source: Sulfolobus solfataricus
• Total number of polymer chains: 6
• Total formula weight: 100159.25

Authors

Ling, H.,Sayer, J.M.,Boudsocq, F.,Plosky, B.S.,Woodgate, R.,Yang, W. (deposition date: 2003-12-31, release date: 2004-03-30, Last modification date: 2023-08-23)

• Primary citation: Ling, H.,Sayer, J.M.,Plosky, B.S.,Yagi, H.,Boudsocq, F.,Woodgate, R.,Jerina, D.M.,Yang, W.; Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.; Proc.Natl.Acad.Sci.USA, 101:2265-2269, 2004; PubMed: 14982998; DOI: 10.1073/pnas.0308332100

Experimental method

X-RAY DIFFRACTION (2.7 Å)