Post-insertion complex of the Y-family DNA polymerase Dpo4 with M1dG containing template DNA

Summary for 2V4Q

Related1S0M 2ASL 2JEG 1RYS 2J6T 1N56 2ATL 1JX4 2C22 2VA2 1S97 2AGQ 2JEJ 2AGO 2ASJ 2ASD 1N48 1JXL 2BQ3 2J6U 2UVU 2AGP 2C2R 1S0N 1S0O 2JEF 2UVW 2BQR 2JEI 2BQU 2AU0 1S9F 2C28 2V9W 2C2E 1RYR 2C2D 2UVV 1S10 2J6S 2BR0 2UVR 2VA3 2V4R 2V4S 2V4T
DescriptorDNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*C)-3', 5'-D(*TP*CP*AP*C M1GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
Functional Keywordsdna-directed dna polymerase, dna-binding, metal-binding, dna replication, mutator protein, nucleotidyltransferase, dna adduct, dna damage, dna repair, transferase, dpo4, m1dg, cytoplasm, magnesium, polymerase
Cellular locationCytoplasm (Probable) Q97W02
Total number of polymer chains3
Total molecular weight51508.53
Eoff, R.L.,Stafford, J.B.,Szekely, J.,Rizzo, C.J.,Egli, M.,Guengerich, F.P.,Marnett, L.J. (deposition date: 2008-09-26, release date: 2009-06-16, Last modification date: 2011-07-13)
Primary citation
Eoff, R.L.,Stafford, J.B.,Szekely, J.,Rizzo, C.J.,Egli, M.,Guengerich, F.P.,Marnett, L.J.
Structural and Functional Analysis of Sulfolobus Solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde-Deoxyguanosine Adduct.
Biochemistry, 48:7079-, 2009
PubMed: 19492857 (PDB entries with the same primary citation)
DOI: 10.1021/BI9003588
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.250171.2%2.7%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution