2VK0

Crystal structure form ultalente insulin microcrystals

Summary for 2VK0

Related1AI0 1AIY 1BEN 1EV3 1EV6 1G7B 1HIQ 1HIT 1HLS 1HTV 1HUI 1IOH 1J73 1JCO 1LKQ 1MHI 1MSO 1OS4 1Q4V 1QIZ 1QJ0 1TYM 1VKT 1W8P 1XDA 1ZNJ 1A7F 1B9E 1EFE 1EVR 1FU2 1FUB 1G7A 1GUJ 1HIS 1IOG 1JCA 1K3M 1KMF 1LPH 1MHJ 1OS3 1QIY 1RWE 1SF1 1SJT 1T0C 1T1K 1T1P 2CEU 2HIU 3AIY 4AIY 5AIY 1T1Q 1TRZ 1TYL 1UZ9 1XGL 1XW7 1ZEG 1ZEH 2AIY 2C8Q 2C8R 2H67 2HH4 2HHO 2VJZ
DescriptorINSULIN A CHAIN, INSULIN B CHAIN, ZINC ION, ... (5 entities in total)
Functional Keywordscarbohydrate metabolism, glucose metabolism, micro focus beamline, insulin, hormone, secreted, micro crystal, cleavage on pair of basic residues, disease mutation, diabetes mellitus
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight12049.09
Authors
Wagner, A.,Diez, J.,Schulze-Briese, C.,Schluckebier, G. (deposition date: 2007-12-14, release date: 2008-09-16, Last modification date: 2011-08-03)
Primary citation
Wagner, A.,Diez, J.,Schulze-Briese, C.,Schluckebier, G.
Crystal Structure of Ultralente--A Microcrystalline Insulin Suspension.
Proteins, 74:1018-, 2009
PubMed: 18767151 (PDB entries with the same primary citation)
DOI: 10.1002/PROT.22213
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.292505.7%15.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution