1SJT

MINI-PROINSULIN, TWO CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP, NMR, 20 STRUCTURES

Summary for 1SJT
DescriptorPROINSULIN (2 entities in total)
Functional Keywordshormone, glucose metabolism, disease mutation, diabetes
Biological sourceHomo sapiens (human)
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Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight5711.46
Authors
Hua, Q.X.,Hu, S.Q.,Jia, W.H.,Chu, Y.C.,Burke, G.T.,Wang, S.H.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 1997-10-09, release date: 1998-03-18, Last modification date: 2011-07-13)
Primary citationBurke, G.T.,Chu, Y.C.,Hu, S.Q.,Hua, Q.X.,Jia, W.,Katsoyannis, P.G.,Wang, R.Y.,Wang, S.H.,Weiss, M.A.
Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
J.Mol.Biol., 277:103-118, 1998
PubMed: 9514738
DOI: 110.1006/jmbi.1997.1574
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation
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PDB entries from 2021-06-16