1SJT

MINI-PROINSULIN, TWO CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP, NMR, 20 STRUCTURES

Summary for 1SJT

DescriptorPROINSULIN (2 entities in total)
Functional Keywordshormone, glucose metabolism, disease mutation, diabetes
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5711.46
Authors
Hua, Q.X.,Hu, S.Q.,Jia, W.H.,Chu, Y.C.,Burke, G.T.,Wang, S.H.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 1997-10-09, release date: 1998-03-18, Last modification date: 2011-07-13)
Primary citation
Hua, Q.X.,Hu, S.Q.,Jia, W.,Chu, Y.C.,Burke, G.T.,Wang, S.H.,Wang, R.Y.,Katsoyannis, P.G.,Weiss, M.A.
Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
J.Mol.Biol., 277:103-118, 1998
PubMed: 9514738 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1997.1574
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers11013.8%36.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures