1SF1
NMR STRUCTURE OF HUMAN INSULIN under Amyloidogenic Condition, 15 STRUCTURES
Summary for 1SF1
Entry DOI | 10.2210/pdb1sf1/pdb |
Related | 2HIU |
Descriptor | INSULIN A CHAIN, Insulin (2 entities in total) |
Functional Keywords | hormone, human insulin, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5817.65 |
Authors | Weiss, M.A.,Hua, Q.X. (deposition date: 2004-02-19, release date: 2004-03-30, Last modification date: 2022-03-02) |
Primary citation | Hua, Q.X.,Weiss, M.A. Mechanism of insulin fibrillation: the structure of insulin under amyloidogenic conditions resembles a protein-folding intermediate J.Biol.Chem., 279:21449-21460, 2004 Cited by PubMed: 14988398DOI: 10.1074/jbc.M314141200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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