1ZEH

STRUCTURE OF INSULIN

Summary for 1ZEH
DescriptorINSULIN, M-CRESOL, ZINC ION, ... (6 entities in total)
Functional Keywordshormone, metabolic role, chemical activity, insulin mutant, cross-link, glucose metabolism, diabetes
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains4
Total formula weight12413.66
Authors
Whittingham, J.L.,Edwards, E.J.,Antson, A.A.,Clarkson, J.M.,Dodson, G.G. (deposition date: 1998-05-01, release date: 1998-12-09, Last modification date: 2011-07-13)
Primary citationAntson, A.A.,Clarkson, J.M.,Dodson, G.G.,Edwards, D.J.,Whittingham, J.L.
Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37:11516-11523, 1998
PubMed: 9708987
DOI: 110.1021/bi980807s
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation
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PDB entries from 2021-06-23