1ZEH

STRUCTURE OF INSULIN

Summary for 1ZEH

DescriptorINSULIN, M-CRESOL, ZINC ION, ... (6 entities in total)
Functional Keywordshormone, metabolic role, chemical activity, insulin mutant, cross-link, glucose metabolism, diabetes
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight12413.66
Authors
Whittingham, J.L.,Edwards, E.J.,Antson, A.A.,Clarkson, J.M.,Dodson, G.G. (deposition date: 1998-05-01, release date: 1998-12-09, Last modification date: 2011-07-13)
Primary citation
Whittingham, J.L.,Edwards, D.J.,Antson, A.A.,Clarkson, J.M.,Dodson, G.G.
Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37:11516-11523, 1998
PubMed: 9708987 (PDB entries with the same primary citation)
DOI: 10.1021/bi980807s
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.5 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers91.1%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution