1KMF

NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES

Summary for 1KMF

• Entry DOI: 10.2210/pdb1kmf/pdb
• Related: 1K3M
• NMR Information: BMRB: 5246
• Descriptor: Insulin (2 entities in total)
• Functional Keywords: hormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 2
• Total formula weight: 5794.59

Authors

Xu, B.,Hua, Q.X.,Nakagawa, S.H.,Jia, W.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2001-12-14, release date: 2002-01-09, Last modification date: 2021-10-27)

• Primary citation: Xu, B.,Hua, Q.X.,Nakagawa, S.H.,Jia, W.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A.; Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.; J.Mol.Biol., 316:435-441, 2002; PubMed: 11866509; DOI: 10.1006/jmbi.2001.5377

Experimental method

SOLUTION NMR