1XW7
Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama
Summary for 1XW7
Entry DOI | 10.2210/pdb1xw7/pdb |
Related | 1EV3 |
Descriptor | Insulin, PHENOL, ZINC ION, ... (6 entities in total) |
Functional Keywords | leu-a30insulin, protein unfolding, insulin receptor, hormone-growth factor complex, hormone/growth factor |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 4 |
Total formula weight | 12053.30 |
Authors | Wan, Z.L.,Huang, K.,Xu, B.,Chu, Y.C.,Hu, S.Q.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2004-10-29, release date: 2005-04-12, Last modification date: 2023-08-23) |
Primary citation | Wan, Z.L.,Huang, K.,Xu, B.,Hu, S.Q.,Wang, S.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A. Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin wakayama Biochemistry, 44:5000-5016, 2005 Cited by PubMed: 15794638DOI: 10.1021/bi047585k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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