2BOK

Factor Xa - cation

Summary for 2BOK

• Entry DOI: 10.2210/pdb2bok/pdb
• Related: 1C5M 1EZQ 1F0R 1F0S 1FAX 1FJS 1FXY 1G2L 1G2M 1HCG 1IOE 1IQE 1IQF 1IQG 1IQH 1IQI 1IQJ 1IQK 1IQL 1IQM 1IQN 1KSN 1KYE 1LPG 1LPK 1LPZ 1LQD 1MQ5 1MQ6 1MSX 1NFU 1NFW 1NFX 1NFY 1NL8 1P0S 1V3X 1XKA 1XKB 2BMG 2BOH
• Descriptor: COAGULATION FACTOR X, [AMINO (4-{(3AS,4R,8AS,8BR)-1,3-DIOXO-2- [3-(TRIMETHYLAMMONIO) PROPYL]DECAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL}PHENYL) METHYLENE]AMMONIUM, SODIUM ION, ... (5 entities in total)
• Functional Keywords: serine protease, coagulation factor, cation, inhibitor, egf- like domain, hydrolase, plasma, protease
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 33655.31

Authors

Morgenthaler, M.,Schaerer, K.,Paulini, R.,Obst-Sander, U.,Banner, D.W.,Schlatter, D.,Benz, J.,Stihle, M.,Diederich, F. (deposition date: 2005-04-12, release date: 2005-06-16, Last modification date: 2023-12-13)

• Primary citation: Scharer, K.,Morgenthaler, M.,Paulini, R.,Obst-Sander, U.,Banner, D.W.,Schlatter, D.,Benz, J.,Stihle, M.,Diederich, F.; Quantification of Cation-Pi Interactions in Protein-Ligand Complexes: Crystal-Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion Ligand; Angew.Chem.Int.Ed.Engl., 44:4400-, 2005; PubMed: 15952226; DOI: 10.1002/ANIE.200500883

Experimental method

X-RAY DIFFRACTION (1.64 Å)