1IOE
Human coagulation factor Xa in complex with M55532
Summary for 1IOE
Entry DOI | 10.2210/pdb1ioe/pdb |
Descriptor | COAGULATION FACTOR XA, CALCIUM ION, (-)-7-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]TETRAHYDRO-8A-(METHOXYMETHYL)-1'-(4-PYRIDINYL)-SPIRO[5H-OXAZOLO[3,2-A]PYRAZINE-2(3H),4'-PIPERIDIN]-5-ONE, ... (4 entities in total) |
Functional Keywords | hydrolase, serine protease, blood coagulation factor, complex |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 2 |
Total formula weight | 37735.15 |
Authors | Shiromizu, I.,Matsusue, T. (deposition date: 2001-03-08, release date: 2003-09-23, Last modification date: 2023-12-27) |
Primary citation | Matsusue, T.,Shiromizu, I.,Okamoto, A.,Nakayama, K.,Nishida, H.,Mukaihira, T.,Miyazaki, Y.,Saitou, F.,Morishita, H.,Ohnishi, S.,Mochizuki, H. Factor Xa Specific Inhibitor That Induces the Novel Binding Model In Complex With Human FXa To be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report