1NFX
CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR208944
Summary for 1NFX
Entry DOI | 10.2210/pdb1nfx/pdb |
Related | 1EZQ 1F0R 1F0S 1NFU 1NFW 1NFY |
Descriptor | COAGULATION FACTOR XA, heavy chain, Coagulation factor XA, light chain, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 2 |
Total formula weight | 44306.48 |
Authors | Maignan, S.,Guilloteau, J.P. (deposition date: 2002-12-16, release date: 2003-02-25, Last modification date: 2023-08-16) |
Primary citation | Maignan, S.,Guilloteau, J.P.,Choi-Sledeski, Y.M.,Becker, M.R.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V. Molecular structures of human Factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket. J.Med.Chem., 46:685-690, 2003 Cited by PubMed: 12593649DOI: 10.1021/jm0203837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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