1F0S
Crystal Structure of Human Coagulation Factor XA Complexed with RPR208707
Summary for 1F0S
Entry DOI | 10.2210/pdb1f0s/pdb |
Related | 1EZQ 1F0R 1F0T 1F0U |
Descriptor | COAGULATION FACTOR XA, CALCIUM ION, THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE, ... (5 entities in total) |
Functional Keywords | protein-inhibitor complex, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 2 |
Total formula weight | 44228.97 |
Authors | Maignan, S.,Guilloteau, J.P.,Pouzieux, S.,Choi-Sledeski, Y.M.,Becker, M.R.,Klein, S.I.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V. (deposition date: 2000-05-17, release date: 2000-09-20, Last modification date: 2024-03-13) |
Primary citation | Maignan, S.,Guilloteau, J.P.,Pouzieux, S.,Choi-Sledeski, Y.M.,Becker, M.R.,Klein, S.I.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V. Crystal structures of human factor Xa complexed with potent inhibitors. J.Med.Chem., 43:3226-3232, 2000 Cited by PubMed: 10966741DOI: 10.1021/jm000940u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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