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1LQD

CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 45.

Summary for 1LQD
Entry DOI10.2210/pdb1lqd/pdb
Related1LPG 1LPK 1LPZ 1LQE
DescriptorBlood coagulation factor Xa, CALCIUM ION, 1-(3-CARBAMIMIDOYL-BENZYL)-4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 3,5-DIMETHYL-BENZYLAMIDE, ... (5 entities in total)
Functional Keywordsprotein-inhibitor complex, blood coagulation factor, serine proteinase, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P00742 P00742
Total number of polymer chains2
Total formula weight44226.00
Authors
Schreuder, H.A.,Loenze, P.,Brachvogel, V.,Liesum, A. (deposition date: 2002-05-10, release date: 2003-05-10, Last modification date: 2011-07-13)
Primary citationMatter, H.,Defossa, E.,Heinelt, U.,Blohm, P.M.,Schneider, D.,Mueller, A.,Herok, S.,Schreuder, H.A.,Liesum, A.,Brachvogel, V.,Loenze, P.,Walser, A.,Al-Obeidi, F.,Wildgoose, P.
Design and Quantitative Structure-Activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa
J.Med.Chem., 45:2749-2769, 2002
Cited by
PubMed: 12061878
DOI: 10.1021/jm0111346
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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